We are in relentless pursuit of breakthroughs that improve patients' lives. We drive innovation each day to make the world a healthier place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more inventive, attract and retain the best people, and know how to harness the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—fuels everything we do and shows our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and reflects the value we work to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We live our purpose by sourcing the best science in the world, working with others in the healthcare system to improve access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.